Significant shareholders:

Shareholder/Beneficial OwnerShares% ISC
Lombard Odier Investment Managers144,679,39014.96
Canaccord Genuity Wealth Management95,926,7619.92
T Rowe Price Global Investments79,524,8078.22
Hargreaves Lansdown, stockbrokers70,643,7497.30
Mr Richard Griffiths60,891,4416.30
Interactive Investor58,388,6406.04
Dr Andrew Nelson*38,835,5144.01
Janus Henderson Investors38,012,5373.93
Artisan Partners31,802,0463.29

as at 31 January 2025

Quoted: AIM (London Stock Exchange)

Other Exchanges / Trading Platforms: The Company is not listed on any other exchanges or trading platforms.

Number of securities in issue: 967,267,966 Ordinary shares.

Shares not in public hands: Insofar as the Company is aware, the percentage of securities that is not in public hands is 15.0%, these being held by directors, their families and significant shareholders.

Own shares held in treasury: The Company holds 4,115 Ordinary Shares in treasury.

Details on any restrictions on the transfer of securities: There are no restrictions on the transfer of securities.

Applicable code(s): The Company is subject to the UK City Code on Takeovers and Mergers. The Code is administered by The Panel and Takeovers in Mergers.

* Per the Company’s RNS announcement of 11 May 2020, 12,121,711 Ordinary Shares of Dr Nelson’s total beneficial interest are subject to a Sale and Repurchase Agreement with Equities First Holdings.